Quoting from official Cyanogen site
Nightlies are not recommended unless you can handle issues arising out of it, since they are not tested
...We have the Nightlies, which are as volatile as a firmware can get. These releases keep coming at an interval of a day or two and if you do end up trying one of these, do not be alarmed if your device goes cuckoo on you. These ROMs are largely untested, and as advised by CyanogenMod, not meant for use for an average user. These releases, are meant to test untested waters that may or may not break your phone
Hence, you should attempt with a stable version, more so when you are trying to install it on Multi ROM