This is true, in most cases, if you plug a USB to aux cable into your phone and connect it to your head unit. Some phones and MP3 players are designed to output audio signals via USB connection, like the original HTC Dream that used a single micro-USB connector for both power and audio output, but most phones and MP3 players come with a standard 3.5mm or 2.5mm TRRS headphone jack for a reason.
Many phones and MP3 players aren’t specifically designed to output sound via their USB connection. The USB connection is capable of transferring digital data back and forth, and can likely also be used to charge the device, but it usually won’t be designed to output an audio signal.
The only case where you would want, or need, to output audio from a phone’s USB connection to an aux input in your head unit is if the phone didn’t also include a headphone jack. Some phones, like the original G1/HTC Dream, omitted a headphone jack in favor of the ability to output sound via the USB connection.
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