Is it safe for me to remove the stock email and calendar applications on from Cyanogenmod ROM? I'm using Gmail and Google Calendar so I don't have need for the stock ones. I could simply disable them but if I removed them entirely, I might be able to save a bit on space on my system partition.
YES, you can delete the stock Email (Email.apk) and stock Calendar (Calendar.apk, CalendarProvider.apk) app. For a list of other apps you can delete on CyanogenMod, see the expandable list at the bottom of the CM wiki.
I'm not so sure for AOSP though.
I've deleted email, calendar, a bunch of other Lenovo (vendor specific), and Google apps with System app deleter and the phone works fine.
I removed the standard CyanogenMod mail app and everything seems to work fine