There's no reason to defragment flash media. It serves no purpose, because access to any flash cell is going to take the same amount of time as access to any other flash cell. The reason defragmenting is beneficial to mechanical hard drives is because it makes related data blocks contiguous, so that they can all be read in order as the disk is spinning and minimizing the amount of movement needed from the drive heads. Flash media has none of these moving parts, and therefore does not suffer from the same problems as mechanical drives.
In fact, defragmenting flash media could potentially be detrimental, because it will wear the memory faster while not providing any benefit. Flash memory firmwares will actually fragment data intentionally, in a practice known as wear-leveling, which helps to prevent specific cells from being overused and wearing out more than others.
Flash-based devices generally benefit from TRIMing, but Android 4.3 or higher will do this for you automatically. Apps that claim to perform defragmentation are suspicious at best. Even if they "work", there is no reason to use them.