I believe you should stick with a max size of 64 kilobytes for the best interoperability. Windows 10 expanded the maximum cluster size from 64 to 2048 kilobytes (2097152 bytes per cluster) in the Spring of 2018.

The open-source world patched util-linux almost immediately to be able to read the partition structures off of such disk, but it will take a while for that to propagate through all Linux-based products (routers, backup software, Android, etc).