From FAQ on Cyanogenmod Forums :
Nightly
These builds are highly experimental. They are the bleeding edge and it is possible for things to break. These are automated builds that are used to test whether the code added to the code base compiles properly. If it does compile, that’s a result. If it doesn’t compile, that is also a result.
The CyanogenMod team releases these builds to the public to allow them to see the progress made. Usually these builds work great and many people use them as “daily drivers”. However, due to the raw nature and the fast-paced development environment of CyanogenMod, things can go wrong. The dev team does not accept official bug reports for these because of the ongoing development.
More Info:
Nightlies are not released as an end product.
What does this mean? It means they are built, automatically and periodically, with no human intervention and no audience in mind whatsoever. They are not verified before being published, and their principal purpose is to compile code and see if it builds on a per device basis. Build failed? That’s a positive result. Build completed? That’s a positive result.
Once a build has gone through all the development and testing phases, the CM team will release the stable builds. After a stable is released, the team goes back to developing nightlies. It is an ongoing process and will always allow you to see the progress that is being made.
Where do I find Stable and Nightly builds for my device?
If your device is officially supported then visit here and choose the build based on your needs from the left pane:
Otherwise, see this link for unofficial ports.